Factores modificables y determinantes asociados un mal control lipídico en individuos con alto riesgo cardiovascular
Issue | Vol. 9 Núm. 3 (2025): Ciencia y Salud, septiembre-diciembre |
DOI | |
Publicado | sep 2, 2025 |
Estadísticas |
Resumen
Introducción:
La ciencia continúa aportando evidencia en el manejo de la enfermedad cardiovascular en pacientes de alto riesgo. Este estudio tuvo como objetivo identificar factores modificables y determinantes sociales de salud asociados al mal control lipídico.
Metodología:
es un estudio observacional y retrospectivo que incluyó 338 historias clínicas de individuos con casos nuevos de infarto al miocardio.
Resultados:
La población fue X(DE)= 68,3 (10,9) años. De las historias clínicas evaluadas, el 48,4% tiene antecedentes de dislipidemia y el 50,3% de Síndrome Coronario Agudo. La probabilidad de sufrir un evento coronario fue del 57,3% en pacientes con HTA (OR=57,3, p<0,001) y con antecedentes de ACV y enfermedad renal crónica (OR=9,10, p=0,038). El 4,2% (n = 11) de los pacientes recibieron monoterapia con estatinas de baja intensidad y ninguno de ellos recibió terapia de alta intensidad combinada con ezetimiba. En el 20,4% (n = 69) de los pacientes se observó una reducción de la dosis del tratamiento y en el 2,1% (n = 7) de los casos se añadió una nueva medicación. Solo el 31,95% (n = 108), p < 0,01, alcanzó niveles de c-LDL inferiores a 70 mg/dl en el período de estudio. Cada punto de aumento en el nivel de colesterol LDL se asoció con un aumento aproximado del 6% en angina inestable/infartos de miocardio en comparación con las categorías de frecuencia más baja.
Conclusión:
Existe una necesidad apremiante de protocolizar y establecer planes de adherencia para reducir los niveles de c-LDL en personas con alto riesgo cardiovascular.
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Afiliaciones
Jenny L. Cepeda-Marte
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Ricardo E. Hernández-Landa
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Carlos Ruiz-Matuk
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Marc B. Bello-Figueroa
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Kristy Polanco
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Daniela Salado
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Valery Carrion
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Jazmin Pantaleon Vásquez
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.
Pedro Vargas Bocio
CEDIMAT Centro de Diagnóstico Medicina Avanzada y Telemedicina. Arturo Logroño, Plaza de la Salud. República Dominicana.
Roberto Garcia
NOVARTIS Pharma CANDEAN, Guatemala City, Guatemala.
Elizabeth Sánchez Almánzar
Universidad Iberoamericana, Francia Street, 208. Santo Domingo, República Dominicana.